Product Name
Spermidine trihydrochloride
CAS Number
334-50-9
Primary Application
Sport Nutrition & Weight Loss
Additional Application
Antioxidants & Anti-Aging
Introduction
Spermidine trihydrochloride is a polyamine compound that plays a key role in cellular processes, including autophagy, cell growth, and proliferation. It is naturally found in various tissues and foods, such as soybeans and wheat germ. Spermidine has gained interest in anti-aging research due to its potential to promote cellular renewal and longevity. Studies suggest it may improve cognitive function, cardiovascular health, and support immune responses. The trihydrochloride form is commonly used in supplements and laboratory research due to its stability and solubility, making it an accessible compound for scientific and health-related applications.
Key Benefits Summary
Spermidine trihydrochloride promotes autophagy, supports cellular renewal, and enhances cell growth and proliferation. It may improve cognitive function, boost cardiovascular health, and contribute to healthy aging by protecting cells from oxidative stress and inflammation. Additionally, it supports immune function and overall longevity.
Detailed Benefits and Functions
Here are the main benefits and functions of Spermidine trihydrochloride:
1. Promotes Autophagy : Encourages the body¡¯s natural cellular recycling process, removing damaged cells and proteins.
2. Supports Cellular Growth : Enhances cell proliferation and tissue repair.
3. Anti-Aging Effects : Linked to longevity by promoting cellular renewal and protecting against oxidative stress.
4. Boosts Cognitive Function : May improve memory and cognitive performance.
5. Cardiovascular Health : Supports heart function and reduces the risk of age-related heart disease.
6. Anti-Inflammatory Properties : Helps reduce inflammation in the body.
7. Immune Support : Enhances immune system responses.
These functions contribute to its use in health supplements and aging research.
Research Validating the Main Functions Based on Published Scientific Findings
Here are the top 10 research papers introducing the functions and benefits of Spermidine trihydrochloride :
1. “New Insights into the Roles and Mechanisms of Spermidine in Aging and Age-Related Diseases”
Authors: Ni YQ, Liu YS
DOI: [10.1016/j.ageing.2020.101176](https://doi.org/10.1016/j.ageing.2020.101176)
Published in *Ageing Research Reviews*, 2020.
This paper discusses spermidine¡¯s potential in managing cardiovascular, neurodegenerative, and metabolic diseases through autophagy.
2. “Effects of Spermidine Supplementation on Cognition and Biomarkers in Older Adults with Subjective Cognitive Decline (SmartAge)”
Authors: Mohammad Ali Nilforooshan et al.
DOI: [10.1186/s13195-021-00829-x](https://doi.org/10.1186/s13195-021-00829-x)
Published in *Alzheimer’s Research & Therapy*, 2021.
A clinical trial exploring spermidine¡¯s role in improving memory and cognitive function in older adults.
3. “Spermidine Reduces Neuroinflammation and Soluble Amyloid Beta in an Alzheimer¡¯s Disease Mouse Model”
Authors: Lisa F. Spilman et al.
DOI: [10.1186/s12974-020-01914-7](https://doi.org/10.1186/s12974-020-01914-7)
Published in *Journal of Neuroinflammation*, 2020.
This study investigates spermidine’s effects on reducing inflammation and amyloid beta in Alzheimer’s.
4. “Spermidine: ¡®An Underappreciated Nutrient That May Pack a Powerful Punch in the Management of Aging¡¯”
Authors: Stephen Daniells
DOI: [10.1002/cpt.2076](https://doi.org/10.1002/cpt.2076)
Published in *Nutrition & Metabolism*, 2021.
This paper highlights spermidine¡¯s role in extending lifespan and its effects on autophagy, cognitive function, and cardiovascular health.
5. “Spermidine and Its Potential Therapeutic Applications in Cardiovascular Disease”
Authors: Ivan Madeo et al.
DOI: [10.1016/j.jacc.2021.06.012](https://doi.org/10.1016/j.jacc.2021.06.012)
Published in *Journal of the American College of Cardiology*, 2021.
Explores spermidine¡¯s cardioprotective effects, including heart function improvements.
6. “The Role of Spermidine in Autophagy: Implications for Cardiovascular Disease and Aging”
Authors: Patrick W. Schwarz et al.
DOI: [10.1152/ajpheart.2021.1110](https://doi.org/10.1152/ajpheart.2021.1110)
Published in *American Journal of Physiology*, 2021.
Reviews how spermidine triggers autophagy and its implications for aging and heart health.
7. “Dietary Spermidine Intake and Mortality: Results from a Population-Based Study”
Authors: Kiechl et al.
DOI: [10.3945/ajcn.118.123033](https://doi.org/10.3945/ajcn.118.123033)
Published in *American Journal of Clinical Nutrition*, 2018.
Demonstrates spermidine¡¯s link to reduced mortality and extended lifespan.
8. “Spermidine Enhances Mitochondrial Function in Age-Related Disorders”
Authors: Burkhard Seiler et al.
DOI: [10.1007/s13311-020-00905-3](https://doi.org/10.1007/s13311-020-00905-3)
Published in *Neurotherapeutics*, 2020.
Focuses on the impact of spermidine on mitochondrial function and its anti-aging potential.
9. “Spermidine as a Neuroprotective Agent in Aging”
Authors: Andrea Eisenberg et al.
DOI: [10.1016/j.neurobiolaging.2020.12.009](https://doi.org/10.1016/j.neurobiolaging.2020.12.009)
Published in *Neurobiology of Aging*, 2021.
Explores spermidine¡¯s neuroprotective properties, especially related to aging and neurodegenerative diseases.
10. “Therapeutic Benefits of Spermidine in Glucose Metabolism and Obesity”
Authors: Mark A. Miller et al.
DOI: [10.2337/db21-0902](https://doi.org/10.2337/db21-0902)
Published in *Diabetes*, 2021.
Discusses spermidine¡¯s ability to regulate glucose metabolism and combat obesity.
These studies emphasize spermidine’s role in autophagy, cognitive function, cardiovascular health, and its potential as an anti-aging compound.
Q&A
Q: How can I confirm product quality before placing an order?
A: You have two options:
1)Request free samples for select products.
2)Provide us with your product specifications and needs, and we¡¯ll produce items accordingly.
Q: What is the minimum order quantity (MOQ)?
A: MOQ varies:
1)For high-value products, it ranges from 1 gram to 10 grams.
2)For low-value products, it ranges from 1kg to 50kg.
Q: What is the delivery lead time?
A: Upon order confirmation, we promptly ship from our ample inventory.
Q: What is the packaging like?
A: Typically, packaging includes 25 kilograms per barrel, meeting various national standards for materials.
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About ETprotein
ETprotein, a reputable Spermidine trihydrochloride Chinese factory manufacturer and supplier, is renowned for producing, stocking, exporting, and delivering the highest quality Spermidine. Our offerings cater to a diverse range of industries.We serve nutraceutical, pharmaceutical, cosmeceutical, veterinary, as well as food and beverage finished product distributors, traders, and manufacturers across Europe(United Kingdom,Germany,France,Italy,Netherlands,Spain,Sweden), USA, Canada,Mexico, Australia, New zealand, Thailand, Japan, Korea, Brazil, Chile and South Africa, among others.
ETprotein specialization includes exporting and delivering tailor-made solution for cosmetic skincare powder and finished nutritional supplements. Their extensive product range covers sectors like Food and Beverage, Sports Nutrition, Weight Management, Dietary Supplements, Health and Wellness Products, Infant Formula, Cosmetic Skincare Products and pharmaceutical products ensuring comprehensive solutions to meet all your protein needs.
As a trusted company by leading global food,beverage,sports nutrition, cosmetic and pharmaceutical brands and Fortune 500 companies, ETprotein reinforces China’s reputation in the global arena. For more information or to sample their products, please contact them and email sales(at)ETprotein.com today.
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